Cannabis, diabetes and HIV/HCV

Cannabis use is associated with a reduced risk of diabetes in patients infected both with HIV and HCV. Diabetes and insulin resistance are frequent in patients who are both infected with the HI virus [HIV] and the hepatitis C virus [HCV]. Researchers from several French institutes found that among 703 patients infected with both viruses those 319 (45%) participants, who reported cannabis use in the 6 months before the first study visit, were less likely to have insulin resistance.

With insulin resistance cells fail to respond to the normal actions of the hormone insulin. The body produces insulin, but the cells in the body become resistant to insulin and are unable to use it as effectively, leading to type 2 diabetes. Authors concluded that “the benefits of cannabis-based pharmacotherapies for patients concerned by increased risk of insulin resistance and diabetes need to be evaluated in clinical research and practice. “

Carrieri MP, Serfaty L, Vilotitch A, Winnock M, Poizot-Martin I, Loko MA, Lions C, Lascoux-Combe C, Roux P, Salmon-Ceron D, Spire B, Dabis F; ANRS CO13 HEPAVIH Study Group. Cannabis use and reduced risk of insulin-resistance in HIV-HCV infected patients: a longitudinal analysis (ANRS HEPAVIH CO-13). Clin Infect Dis. 2015 Mar 16. [in press]

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