Antitumor Effects of Cannabidiol

Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines Daniela ParolaroMaria P. Abbracchio andPaola Massi, Angelo Vaccani, Stefania Ceruti, Arianna Colombo, Abstract Recently, cannabinoids (CBs) have been shown to possess antitumor properties. Because the psychoactivity of cannabinoid compounds limits their medicinal usage, we undertook the present study to evaluate the in vitro antiproliferative ability of cannabidiol (CBD), […]

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CBD and epilepsy

Oral cannabis extracts were effective in one third of children with epilepsy in an open study About one third of children suffering from different forms of epilepsy experienced a more than 50 % reduction in seizures by the use of oral cannabis extracts, researchers at the Medical Campus of the University of Colorado in Denver reported in the journal Epilepsy & […]

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Cannabidiol and bone fracture

Cannabidiol improves bone fracture healing in rats Scientists of the Bone Laboratory of Hebrew University of Jerusalem, Israel, reported that the major non-psychoactive cannabis constituent, cannabidiol (CBD), enhances the biomechanical properties of healing bone fractures in rats. The maximal load capacity, but not the stiffness, of thigh bones from rats given a mixture of CBD and THC for 8 weeks […]

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Cannabis, diabetes and HIV/HCV

Cannabis use is associated with a reduced risk of diabetes in patients infected both with HIV and HCV. Diabetes and insulin resistance are frequent in patients who are both infected with the HI virus [HIV] and the hepatitis C virus [HCV]. Researchers from several French institutes found that among 703 patients infected with both viruses those 319 (45%) participants, who reported […]

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CBD anti-inflamatory

A CBD rich cannabis extract showed better anti-inflammatory effects than pure cannabidiol In experiments with mice a CBD rich cannabis extract was superior in reducing inflammation than pure CBD. This is the result of research by scientists of Hebrew University of Jerusalem, Israel. They used a cannabis strain called Avidekel to prepare extracts, which were given either orally or injected […]

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Cannabidiol anticancer

Cannabidiol as potential anticancer drug. Massi P1, Solinas M, Cinquina V, Parolaro D. Abstract Over the past years, several lines of evidence support an antitumourigenic effect of cannabinoids including Δ(9)-tetrahydrocannabinol (Δ(9)-THC), synthetic agonists, endocannabinoids and endocannabinoid transport or degradation inhibitors. Indeed, cannabinoids possess anti-proliferative and pro-apoptotic effects and they are known to interfere with tumour neovascularization, cancer cell migration, adhesion, invasion and metastasization. However, the clinical […]

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